Artificial Intelligence in Healthcare Companies
We analyzed the enterprise AI use cases of 9 healthcare companies to understand trends, impact, and insights.
Healthcare companies' adoption of AI
Overview
UnitedHealth has rapidly expanded its use of AI, reaching over 1,000 AI applications by mid-2025, spanning claims processing, call routing, clinical data summarization, and member experience enhancement under CTO Sandeep Dadlani's leadership.
McKesson has steadily integrated AI across its healthcare supply chain and oncology data management, moving from early digital infrastructure investments (2019) to advanced collaborations leveraging large language models and real-world data analytics by 2025.
Cigna has progressively integrated AI technologies from 2019, initially focusing on patient medication adherence and data analytics to improve patient outcomes, evolving to deploying advanced AI-powered digital tools that enhance customer experience by 2025, including a generative AI virtual assistant with over 80% user helpfulness and broad adoption across its myCigna portal.
Cardinal Health has progressively integrated AI into its oncology insights, clinical decision support, supply chain management, and pharmaceutical distribution from 2019 through 2025, featuring products like the Navista AI suite and Jvion CORE to enhance patient care and operational efficiency.
Elevance Health has steadily expanded its AI-enabled healthcare services and internal capabilities from 2023 through 2025, including scaling digital concierge care to 40,000 members, employing AI for diagnostics, call center efficiency, and personalized patient outreach, and integrating AI into core operations to improve outcomes for over 109 million consumers.
HCA Healthcare has progressively expanded its adoption of AI technologies from initial pilots in 2023, including partnerships with Google Cloud to deploy generative AI tools in hospitals and emergency rooms, to widespread operational and clinical AI integration through 2025.
Johnson & Johnson has strategically transitioned from broad AI experimentation, managing nearly 900 use cases, to focusing on high-impact areas such as surgical automation, drug discovery, and supply chain optimization by 2025, partnering with key players like Nvidia and Quantum Pharma.
Merck has progressively integrated advanced AI, including generative AI and machine learning, across its drug discovery, development, and clinical processes between Q4 2023 and Q3 2025, exemplified by collaborations with Vector Institute, Variational AI, and BCG, highlighting leaders like Dr. Iya Khalil and CEO Robert Garbaccio.
Pfizer has progressively integrated AI since 2014, pioneering AI-driven drug discovery with key milestones including the rapid development of the COVID-19 vaccine and oral antivirals like Paxlovid, achieving up to 40% faster preclinical milestones and 12% reduction in clinical trial failure rates. Collaborations with startups like PostEra and institutions such as CeMM and XtalPi have advanced AI-driven molecule and small molecule chemical space exploration.
46 Use Cases in Healthcare
| Company | Use Case |
|---|---|
| Elevance Health | Personalized Outreach Leveraging AI to send personalized and direct patient alerts and communications via text, app, and email to close care gaps and improve health outcomes. agentic |
| Elevance Health | Claims Automation Elevance applies AI to unify and automate claims processing workflows to reduce administrative burden, increase efficiency, and control healthcare costs. traditional |
| Johnson & Johnson | Remote Monitoring Johnson & Johnson applies AI-enabled remote patient monitoring systems to improve ongoing patient care and clinical trial data collection, facilitating more personalized treatments and timely intervention. agentic |
| Pfizer | Clinical Trial Management Pfizer leverages AI to oversee clinical trial data, enhance feasibility predictions, recruitment effectiveness, and cost control by utilizing adaptive algorithms informed by internal study data and real-time learning. traditional |
| Elevance Health | Clinical Decision Support Using AI embedded into the Health OS platform to assist providers with prior authorization workflows and clinical decision-making to improve care delivery efficiency. agentic |
| HCA Healthcare | Operational Efficiency AI-enabled predictive analytics optimize hospital staffing and workflows, ensuring appropriate nurse-to-patient ratios and reducing inefficiencies in operations, leading to better patient outcomes and cost savings. agentic |
| Cardinal Health | Supply Forecasting Integration of AI-driven demand forecasting and predictive analytics in Cardinal Health's pharmaceutical distribution and supply chain management optimizes inventory levels, reduces waste, and prevents stockouts. traditional |
| Cigna | Claims Accuracy Cigna's AI-driven evaluation and management coding policy automatically downcodes high-level claims without review, aiming to reduce inaccurate payments and administrative burden but raising concerns about clinical judgment being undervalued. traditional |
| Cigna | Cardiovascular Imaging Cigna covers AI-powered coronary plaque analysis software (HeartFlow and Cleerly), using advanced imaging AI to improve diagnosis and treatment of cardiovascular disease, enhancing clinical outcomes and cost efficiency. traditional |
| Elevance Health | AI Skillbuilding Elevance is investing in AI fluency training and certification programs for employees, partnering with OpenAI and universities to build AI skills that support innovation and operational excellence. traditional |